Areas and Platforms

ECCPS Structure

The ECCPS is organized into nine Research Areas and complemented by three Platforms. Our scientific goals: we are dedicated to identifying molecular mechanisms and developing new therapeutic strategies to combat cardiopulmonary disease in an interdisciplinary and translational approach. In the second phase starting in 2012, ECCPS includes a new international Research Area (Area K), focusing on pulmonary vascular diseases of particular relevance to resource-poor areas of the world.

Research Areas / Platforms

A Stem/progenitor cells in development, repair and therapy

Project Leader (Location):

S. Dimmeler (GU)
T. Braun (MPI-BN)


B Vascular remodelling and reverse remodelling

Project Leader (Location):

F. Grimminger (JLU)
R.T. Schermuly (JLU)


C Angiogenesis and alveogenesis

Project Leader (Location):

K.H. Plate (GU)
S. Bellusci (JLU) 


D Matrix regulation and fibrosis

Project Leader (Location)

A. Günther (JLU)
L. Schäfer (GU)


E Redox regulation: ischemia, hypoxia, and reactive oxygen species 

Project Leader (Location)

R.P. Brandes (GU)
N. Weissmann (JLU)


F Barrier integrity during inflammation and repair

Project Leader (Location)

J. Lohmeyer (JLU)
R.E. Morty (MPI-BN)


G Endocrine Vascular Interface

Project Leader (Location):

I. Fleming (GU)
K.T. Preissner (JLU)


I Molecular signature analysis for individualised therapy

Project Leader (Location)

C. Hamm (Gi/BN)

A. Ghofrani (Gi)


K Pulmonary hypertension associated with infectious diseases and high altitude

Project Leader (Location):

A. Ghofrani (JLU)
M.R. Wilkins (ICL, UK)


Platform A Techniques and technology development

Project Leader (Location):

R. P. Brandes (GU)
R.T. Schermuly (JLU)


Platform B Translation of basic science into clinical studies and commercial exploitation

Project Leader (Location):

G. Geisslinger (GU)
A. Günther (JLU)


Platform C Education and Training

Project Leader (Location):

D. Steinhilber (GU)
W. Kummer (JLU)

GU: Goethe-University Frankfurt, JLU: Justus-Liebig-University Giessen, MPI-BN: Max-Planck-Institute Bad Nauheim

Note: All figures in Research Areas courtesy of