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2016

2016

J Clin Invest. 2016 Dec 1; 126(12):4527-4536.

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release.

The ability of endothelial cells, the inner lining of blood vessels, to respond to shear stress exerted by blood flow is crucial for the development...

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Nat Med. 2016 Oct; 22(10):1140-1150.

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.

Atherosclerosis is a chronic vascular inflammatory disease. The clinical manifestation of atherosclerotic disease remains the major cause of morbidity...

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Proc Natl Acad Sci U S A. 2016 Oct 4; 113(40):11237-11242

Fast revascularization of the injured area is essential to support zebrafish heart regeneration.

A heart attack occurs when blood flow is blocked and oxygen is unable to reach the heart, finally leading to damaged cardiac muscle cells. Dead muscle...

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